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Alicia Woock

Alicia Woock
Education:

Appalachian State University, B.S. with honors in Chemistry
Hometown: New Bern, NC
PhD Advisor: Charles Clevenger, MD, PhD
Graduate Program: CCTR/CMM (Pathology)

 

Research Interests:

Alicia's research interests lie in proteins/receptor systems in various pathologies. Her undergraduate honors thesis studied xenobiotic export from the body focusing on organic anion transport in the Caenorhabditis elegans model using fluorescence microscopy. Her research experience continued after graduating at the National Institute of Mental Health in a translational laboratory focused on radioligand development for PET imaging of various neurological disorders. She is now working in Dr. Clevenger's laboratory to elucidate cellular signaling of the prolactin/prolactin receptor signaling cascade in breast cancer to understand how this signaling cascade regulates cancer progression and metastasis. Ultimately, Alicia wants to build clinical trials  to develop diagnostic and treatment options for cancer patients. 

Personal Bio:

Alicia was born and raised in New Bern, NC, the colonial capital of the state. She attended Appalachian State University where she developed her passion for snowboarding and the mountains. She enjoys spending time cooking vegetarian dishes and baking, trying out her green thumb, art, live music, and exploring all Richmond has to offer in her down time.

Professional, Leadership, and Service Activities:

Current Treasurer for the American Physician Scientists Association Chapter at VCU (APSA @ VCU)

Former Co-President of the VCU School of Medicine Student Interest Group in Neurology (SIGN)

Publications:

Hong J, Lu S, Xu R, Liow JS, Woock AE, Jenko KJ, Gladding RL, Zoghbi SS, Innis RB, Pike VW. [carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain. Nucl Med Biol. 2015 Dec;42(12):967-74.

Kreisl WC, Bhatia R, Morse CL, Woock AE, Zoghbi SS, Shetty HU, Pike VW, Innis RB. Increased Permeability-Glycoprotein Inhibition at the Human Blood-Brain Barrier Can Be Safely Achieved by Performing PET During Peak Plasma Concentrations of Tariquidar. J Nucl Med. 2015 Jan;56(1):82-7.

Xu, R.; Zanotti-Fregonara, P.; Zoghbi, S.S.; Gladding, R.L.; Woock, A.E.; Innis, R.B.; Pike, V.W. Synthesis and Evaluation in Monkey of a Promising Radioligand for PET Imaging of Brain mGluR1 In Vivo: [18F]FIMX. J Med Chem. 2013; 56 (22): 9146.