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Ryan Mischel

Ryan MischelEducation:

University of North Dakota, B.S. in Biology/Pre-Health
Hometown: West Fargo, ND
PhD Advisor: Hamid Akbarali, PhD
Graduate Program: Pharmacology and Toxicology


Research Interests:

Ryan’s research background and training have primarily involved electrophysiology.  He spent two years during undergrad in a neuroscience laboratory investigating how selective activation of adrenergic receptor subtypes modulates hippocampal neurogenesis and epileptogenesis. In the process, he was familiarized with whole tissue field potential recordings and numerous behavioral mouse models. His PhD dissertation will investigate the role of gastrointestinal microbiota in morphine tolerance of dorsal root ganglion nociceptors. He will utilize whole-cell current- and voltage-clamp techniques to quantify morphine responses and characterize ion channel kinetics in these cells.

Personal Bio:

Ryan was born and raised in Fargo, ND. He graduated summa cum laude from the University of North Dakota in 2012 with a BS in Biology/Pre-Medicine. His clinical interests include cardiology, neurology, and psychiatry. Much of his leisure time is spent exploring interests in distance running, music production, philosophy, statistics, and quantum mechanics.

Honors, Awards, and Grants:

F30 Fellowship (2017)
    Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship
    National Institutes of Health - National Institute on Drug Abuse (NIDA)
    Role of gastrointestinal microbiome in opioid tolerance
    F30 DA042542-01A1
Phi Kappa Phi Honor Society (2016)


Mischel, RA and Smith, TH (2017). Chapter 9: Gastrointestinal Drugs. Drugs and Their Actions (3rd Edition). 67-78. Acton, MA: XanEdu.

Mischel, RA and Smith, TH (2017). Chapter 21: Drugs for the Major Psychiatric Disorders. Drugs and Their Actions (3rd Edition). 156-169. Acton, MA: XanEdu.

Smith, TH and Mischel, RA (2017). Chapter 31: Cannabinoids. Drugs and Their Actions (3rd Edition). 214-218. Acton, MA: XanEdu.

Kang, M*, Mischel, RA*, Bhave, S, Komla, E, Huang, C, Dewey, WL, and Akbarali, HI (2017). The effect of gut microbiome on tolerance to morphine mediated antinociception in mice. Scientific Reports. doi:10.1038/srep42658 *Equal contribution first-author